Using Skype for Business Server Management Shell to remove a user Hit 'Edit' under Product Licenses, choose the license type and deselect Skype for Business under the listed applications. From Office 365, go to the Office 365 Admin portal, then Active Users and select the user you want to delete. Removing a user on a basic level is a pretty simple task. Here, we explain how to remove a user from Skype for Business. So if you want to discontinue using Skype For Business or want to remove a user that, for example, may no longer work for the company anymore, you can do so in a variety of ways. This isn't to mention the mind-numbing plight of low-quality video and frustrating connectivity issues. A host of small but irritating bugs, meanwhile, that have arisen over the years could be enough to put somebody off entirely. Functionality, too, may suffer in some instances, including an inability to call landlines for some users.